He writes:
Could D-Mannose Benefit Your Gastrointestinal Health?
*With D-mannose, many people first think of urinary tract health. However, this unique sugar may offer other potential benefits as well.
Some studies suggest that D-mannose may be useful as a “prebiotic.” Prebiotics are substances that promote the growth of beneficial bacteria in your gut. The proper balance between “good” and “bad” bacteria is a prerequisite for both gut and overall health, so D-mannose may support your health by helping to raise levels of good bacteria.*
Similar to how D-mannose works in your urinary tract, pathogenic bacteria are attracted to D-mannose on tissue cell membranes in your gut. D-mannose naturally occurs in the cells that line the walls of your urinary tract.
There is also evidence that D-mannose may help protect against lectins in your gastrointestinal tract. Lectins are proteins found in beans, seeds, grains, and even some vegetables and fruits. They present a challenge to digestion because they are not broken down by stomach acid or digestive enzymes.
Studies show that D-mannose may help bind and block lectins, and prevent them from reacting with and damaging your intestinal wall.*
So, if I am understanding this, it sounds like the d-mannose is removing the bacteria, and not killing it. This sounds like it would not cause the die-off that so many products cause. This sounds like some kind of miracle cure!
In the past I have used d-mannose daily for months on end, and I have not seen an improvement in my symptoms from it. However, it does seem to work for bladder health, and can get rid of, and treat bladder infections for me.
So, the question is, what would be the appropriate dose that could make a difference in IBS or SIBO? This is not something I could find on the internet in any definitive form. But, one article said, "In some lab studies and studies in mice, D-mannose components were shown to increase the growth of "good" bacteria. This suggests D-mannose may have some use for people with dysbiosis, an imbalance in good and bad bacteria."
Has d-mannose ever worked for you for intestinal health? What dosage did you use?
Has d-mannose ever worked for you for intestinal health? What dosage did you use?
D-Mannose is absorbed from the small Intestine and very little reaches the Cecum and Colon where the GI tract benefits may occur. It may be better to consume a "Polymeric" source of Mannose that remains intact in the small intestine and can be broken down by the Microflora into Mannose in the Colon. This type of polymer is found in Yeast Cell Walls and is called MannanOligosaccharide. Yeast cell walls are widely used in Animal Husbandry instead of Antibiotics and appear to act as Prebiotics (food for good Bacteria) and Binding to Pathogenic Bacteria like Adherent Invasive E Coli. There are many products available.One such product is called SAfmannan (French). There is a Yeast cell wall product available in the US for Human us. It is called EPICOR prebiotic. Mannans are also found in Fenugreek seeds and Konjac powder.
ReplyDeleteThank you. That was fascinating! I have also used Epicor, but did not realize these things about it.
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