FUT2 defect involved in Crohn's disease

https://metabolichealing.com/fut2-gene-mutations-your-gut-flora/

Many people with Crohn's disease have a FUT2 gene defect. This article says that it causes problems in the ability to create prebiotics for gut flora and a predisposition toward Crohn's disease. Also it causes elevated B-12 levels. People with this defect have problems with gut diversity.

Histamine Intolerance

Histamine Intolerance occurs with many people with Crohn's disease because of the intestinal dysbiosis going in the gut. This article from Natural News describes symptoms describes Histamine Intolerance and says that people with IBS and Crohn's disease have it more commonly.

http://www.naturalnews.com/047470_DAO_enzymes_histamine_intolerance_immune_system.html

This article also talks about histamine intolerance.

http://naturimedica.com/histamine-intolerance-causes-treatment/

Sadly, many of these articles talk about avoiding kefir, sauerkraut, bone broth, and even probiotic supplements. All of these of course are foundational to the GAPS diet, which many people are trying to follow for their Crohn's disease.

Investigation into Management of Angioedema caused by Intestinal Bacteria

This article shows the drug control flowchart that should occur for people with chronic angioedema. It says to start out with a long acting antihistamine like claritin and then add a secondary one like hydroxyzine if that is not enough.

http://www.aafp.org/afp/2004/0301/p1123.html

It also talks about how chronic angioedema can be related to bacterial and parasitic infections and that it is more common in women than men.

An article about angioedema has this statement, "Helicobacter pylori, a type of bacteria found in the stomach, can trigger abdominal attacks. Antibiotics to treat the bacteria help decrease abdominal attacks."

An article about histamine intolerance talks about how gut dysbiosis and having too many of the wrong kinds of bacteria can cause angioedema.

http://naturimedica.com/histamine-intolerance-causes-treatment/

The Briggs Protocol

Last night we learned about something new which we had never heard of...which is surprising because we have been at this for awhile. While perusing the Facebook page of FMT & Bacteriotherapy Discussion, I came across the Briggs Protocol.

http://thepowerofpoop.com/briggs-protocol/  This is an edited version, not written by him.

http://thepowerofpoop.com/wp/wp-content/uploads/2015/07/IBD-Briggs-July-21-2015-1-1.pdf  

This is his full document.

His three step protocol is:

1. Induce remission
2. Heal the Gut Wall
3. Maintain the Gut Wall

This is what most protocols aim to do of course, but for me what was surprising was the mention of Welbutrin (bupropion), a psychiatric drug that is like Prozac, that can act as a TNF inhibitor like Entyvio. He also recognizes that inflammation must be reduced in order for healing to occur. For myself, I know that my progress toward healing is greatly hindered by the overwhelming reactions to anything that touches my gut flora. So I am interested.

Mr. Briggs with his family

About this blog

This blog examines current ideas on treatment of Crohn's disease. Although the medical community will tell you that diet doesn't matter, or that alternative treatments are worthless for treating Crohn's disease, this is only because there hasn't been as much double blind clinical testing for most alternative treatments. Therefore they cannot with certainty offer them to you. But, the truth is, many treatments can have an effect on Crohn's disease. And, anything that improves your health status is going to have an effect on your Crohn's disease and improve your health.

This blog is meant to create an interactive dialog about this topic, so please comment, and share your experiences and knowledge about the topics at hand.